Journal of Molecular and Cellular Cardiology


PURPOSE: Nitric Oxide (NO) is an important messenger in numerous biological processes, such as the development of new blood vessels, low oxygen vasodilation, and cardio protection. Interventions that can increase NO bioavailability have significant therapeutic potential. The use of far red and near infrared light (R/NIR) can reduce tissue damage, protect neurons from methanol toxicity, and stimulate blood supply.

The researchers examined if R/NIR light could facilitate the release of NO from nitrosyl heme proteins. In addition, they examined if R/NIR light could enhance the protective effects of nitrite on ischemia and reperfusion injury in the rabbit heart.

RESULTS: The outcomes R/NIR light can release NO, and that this released NO may enhance the cardioprotective effects of nitrite.